Our Approach

Targeted protein degradation (TPD) technology
  • Inherits advantages of traditional small-molecule drugs
  • Targets previously "undruggable" complex proteins (e.g., scaffold proteins)
  • Significantly expands potential drug target scope
  • Unique catalytic property enables repeated degradation cycles
  • Supports lower doses, reducing potential side effects
Core technology -ASTRIDE® design platform

Pamplona's ASTRIDE® platform delivers major breakthroughs through deep integration of TPD technology with AI algorithms

Dynamic macromolecular modeling
Full coverage of ubiquitination complexes
Accurate ubiquitination prediction